Combined product has analgesic, antipyretic and anti-inflammatory effect. Metamizole sodium (analgin) which is a non-steroidal anti-inflammatory agent, pyrazolone derivative. It has analgesic and antipyretic properties and antispasmodic effect on the smooth muscles of biliary and urinary tract, muscles of the uterus. Paracetamol is a non-narcotic analgesics which blocks cyclooxygenase (COX), mainly in the central nervous system that effects the centers of pain and of thermoregulation; it has analgesic and antipyretic effect. Caffeine stimulates the psychomotor centers of the brain, has analeptic action facilitates penetration through the blood-brain barrier analgesics and prevents collapses, exciting vasomotor center, eliminates the sedative effects of other components of the medicine.
Phenobarbital in the composition of the drug has a sedative, antispasmodic and muscle relaxant action potentiates the analgesic activity of the components.
Codeine is central action antitussive, phenanthrene alkaloid series belongs to the group of narcotic analgesics. It reduces the excitability of the cough center, has analgesic effect. In small doses does not cause depression of the respiratory center, do not interfere with the function of the ciliated epithelium and reduces bronchial secretions. It enhances the effect of analgesics, hypnotics and sedatives.
Pharmacotherapeutic group: Analgesics. Other analgesics and antipyretics. Pyrazolones. Metamizole sodium, combination with psycholeptics.
ATC code N02B B72.
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