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Substance (API)

Levana

A partial (incomplete) selective agonist of the GABA-A receptor complex, belonging to the benzodiazepine derivatives group. It produces pronounced hypnotic, anxiolytic, moderate muscle relaxant, and anticonvulsant effects; enhances the action of hypnotics, narcotic and neuroleptic drugs, and ethyl alcohol. A unique feature of its hypnotic effect is the ability to increase the duration of both slow-wave and paradoxical sleep, without changing the number of episodes — making its action more physiological and restorative.

Characteristics

Trade name: Levana®

Synonym: Levana*

Chemical name: mono-[7-bromo-2-oxo-5-(2-chlorophenyl)-2,3-dihydro-1H-benzo[1,4]-diazepin-3-yl]succinate monohydrate

Dosage form: powder (substance)

Field of application: manufacturing of non-sterile dosage forms

Description: white or almost white crystalline powder

Registration number: UA/10775/01/01

Marketing authorization validity: unlimited since 25.02.2020

Shelf life: 3 years